© Pint of Science, 2024. All rights reserved.
How are new drugs discovered? Join Pint of Science for an evening of talks exploring research taking place right here in Norwich - and how it is contributing to the future discovery of cures. Local scientists will share stories from their cutting-edge work developing new anti-cancer drugs, the importance of metals in drugs and how microbes can be both good and bad for our life on Earth. Come and enjoy an evening of exciting new research, over a pint or two!
Fluorescent Medicine - Visualising the Prevention of Cancer Metastasis
Dr Isabel Hamshaw (Lecturer in Pharmacology, University of East Anglia)
The C−X−C chemokine receptor 4, CXCR4, is a cell surface receptor that promotes cancer metastasis leading to poor patient survival. Novel medicinal drugs called CXCR4 antagonists can bind and block this receptor, preventing the spread of cancer around the body. Despite many scientists looking into this field, many CXCR4 antagonists fail in clinical trials. The aim of my research is to develop fluorescent CXCR4 antagonists to visualise and better understand CXCR4 driven cancer metastasis.
Microbes - The Good, the Bad, and the Ugly
Professor Arasu Ganesan (Professor in Chemical Biology, University of East Anglia)
Microorganisms can be deadly to humans, as we discovered with the COVID-19 pandemic. However, we are also heavily reliant on microorganisms in a positive sense. Life on earth would not exist without their contribution and in the talk I will give examples of the Good, the Bad and the Ugly in the microbial world.
Metal based drugs - the future of medicine?
Dr Rianne Lord (Associate Professor in Inorganic Chemistry, University of East Anglia)
This talk will provide insights into current and emerging drug developments, especially those which are based on metals. It will highlight their role in the body, effects on patients and how chemists can tune their chemical environment for targeting different diseases.
Map data © OpenStreetMap contributors.