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This night, sponsored by Kidney Research UK pivots around understand how Bristol researchers are working to treat one of the most common causes of kidney disease. Please note that this event has limited access for people with restricted mobility; contact [email protected] for more information.
The breakdown of the kidney filtration system
Nephrotic Syndrome is a devastating disease usually first diagnosed in young children where the kidney filtration system breaks down. This leads to massive loss of proteins from the blood into the urine, with severe long-term complications and eventual kidney failure. The focus of Gavin’s work is to understand the molecular basis of this disease, including inherited forms, and forms caused by circulating toxic factors in the blood.
Podo-what? – what the podocyte is and what it does in the kidney
Carl spent his Kidney Research UK sponsored PhD studentship looking at one of the 20 cell-types in the kidney: the podocyte. In particular, he was looking at how these cells change in kidney disease. Since finishing his PhD he has continued working with Gavin looking at how the circulating factor might be causing kidney disease.