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The human immune system protects our bodies from invaders. Regulation of the immune system is critical for our lives. This evening features talks on the regulation of immune system and how it relates to the development and new treatments of infections and diseases.
Regulatory T cells: the T-Rex of the immune system
Dr Andrea Manrique-Rincón (Postdoctoral fellow at CIITD, Department of Medicine University of Cambridge)
Life is all about balance and the same is true inside the body! Your immune system needs to be able to know what is dangerous for this to be eliminated and what shouldn’t be attacked. A key part of regulating this balance are regulatory T cells (Tregs). Their main job is to prevent your body from overreacting to dangers and calming everything down. However, when this goes wrong the body can attack itself giving rise to autoimmune diseases or prevent a strong response as it happens in cancer. That is why the Tregs are the gigantic masters of equilibrium. Come to learn more about them!
The immune system in sepsis, how complexity kills
Dr Andrew Conway Morris (MRC Clinician Scientist and Consultant in Intensive Care Medicine, Dept of Pathology, University of Cambridge)
This talk will discuss sepsis, which is where the body’s own immune system damages the patient’s organs whilst attempting to fight infection. Starting from an introduction to the immune system, it will explore how infection stimulates the immune system. It will describe how a complex series of interactions lead to a ‘worst of all possible worlds’ where the body’s immune system both attacks organs but also impairs itself so that it cannot fight invading microbes. It will discuss how this situation manifests itself in daily practice in the intensive care unit and the developing treatments.
Other The Castle Bar events
2022-05-11 Our Genes: Past, Present, and Future The Castle Bar 37 St Andrew's Street, Cambridge, CB2 3AR, United Kingdom
Our Genes: Past, Present, and Future
2022-05-10 Focusing on the 3Rs to replace, reduce and refine animal research The Castle Bar 37 St Andrew's Street, Cambridge, CB2 3AR, United Kingdom