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Did you know that cancer has a 'sweet tooth'? And did you know we can now selectively cut and chop DNA inside a cell like never before? Come join us for an exciting night of talks where we will consider how a cancer’s ‘sweet tooth’ allows tumour cells to adapt, proliferate and survive and why we need to exercise and cut the calories. We will also discuss how manipulating our DNA could be used as a tool against cancer and ageing. During the event, there will be Pint of Science goodies to be won and a phenomenal dance interlude...
Diabetes, obesity and bowel cancer: too much sugar in the blood?
Hannah Thompson
(PhD student in Cancer Genetics)
Type 2 diabetes (T2D) and obesity are linked to an increased chance of bowel cancer and a poorer response to treatment. Today, we face a global epidemic of obesity and T2D in an increasingly younger population and a rise in numbers of bowel cancer cases. There are compelling financial, scientific and clinical reasons to investigate links between obesity/T2D and bowel cancer. This talk will consider how a cancer’s ‘sweet tooth’ allows tumour cells to adapt, proliferate and survive and why we need to exercise and cut the calories.
Genetic Puppetry
Dr Gabriella Ficz
(Lecturer in Haemato-Oncology)
One of the most exciting scientific developments since the discovery of the DNA and the polymerase chain reaction is the CRISPR/Cas9 tool. Today we can selectively cut and chop DNA inside a cell like never before. But can we use this tool for other purposes? Like turning genes on and off like a light switch? In any cell in the body we want to? Our lab has embarked in answering these questions and we will discuss how we can manipulate our epigenome to control cell identity and whether in the future we will be able to deliver these tools as therapies against cancer and ageing.
The C Word
A. Joseph, B. Stanford, K. Radley, L. J. Moore, S. Mason, T. Brew
(Performers)
L. J. Moore
(Director)
Ludovico Einaudi
(Music)
The C Word is about the factual occurrence and the physical and mental challenges of cancer. The choreography explores the battle on the body and the unity of support that surrounds this obstacle. Choreographic material has been developed through engaging in conversational experiences and in-depth research into how human cells mutate. The dancers have embodied the idea of mutation and the manipulation of surrounding cells disrupting the normal cell functions.
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