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Many of us will have heard of leukaemia, but how much do we really know about this disease? The presenters will give an interesting insight into scientific research exploring the mechanisms behind acute myeloid leukaemia and seeking greater benefits from treatment.
Future treatments for leukemia: immune checkpoints point the way
Dr Steven Coles (Senior Lecturer in Biochemistry )
Acute myeloid leukaemia is a challenging blood cancer, particularly for the elderly patient, for whom long term remission is generally not durable. Our recent work shows that immune checkpoints play an important role in patient prognosis. This talk will focus on two of these checkpoints “CD200” and “PD-L1” and highlight how targeting these within treatment may be therapeutically beneficial for our patients.
Not all antioxidants are good for you...
James Hillier (PhD student)
Many people are familiar with the idea of antioxidants like vitamin C which may help cells stay healthy by mopping up damaging particles known as free radicals. The idea that there are many other molecules, including proteins that have an antioxidant capacity is less well known. Perhaps counter intuitively these proteins often exist at higher levels in many cancers and may help the cancer cell control it's fate. Consequently targeting these antioxidant proteins may provide a new way to treat these cancers.