© Pint of Science, 2024. All rights reserved.
Join us on Wednesday, September 20th to celebrate National Postdoc Appreciation Week 2023 (NPAW2023) with Pint of Science and SULSA! We have fantastic speakers lined up to talk about their research.
There will be goody bags and refreshments afterwards to encourage networking, kindly sponsored by Proteintech
#NPAW2023 #CelebratePostdocs @proteintech @pintofscience @SULSAtweets
There will be goody bags and refreshments afterwards to encourage networking, kindly sponsored by Proteintech
#NPAW2023 #CelebratePostdocs @proteintech @pintofscience @SULSAtweets
Computational intelligence techniques for Offshore Energy Systems Integration: A Linked Problem Perspective
Dr Akinola Ogunsemi
(National Subsea Centre)
My research entails the investigation of computational intelligence techniques for addressing linked optimisation systems such as supply chains, which considers offshore operational and environmental challenges, and providing strategies for making informed decisions, which contribute to sustainability efforts.
Fibrinogen replacement therapy for traumatic coagulopathy; does the source matter?
Dr Gael Morrow
(School of Pharmacy & Life Sciences)
Traumatic injury accounts for 4.9m deaths globally each year and >25% of patients with severe traumatic injury die from uncontrolled bleeding. To understand the mechanisms of traumatic bleeding, we need to understand what causes uncontrolled bleeding at a molecular and cellular level. There are two key changes that underpin major bleeding in trauma: excessive blood clot breakdown (hyperfibrinolysis) and low levels of the key clotting factor, fibrinofibrinogen (hypofibrinogenaemia). Understanding the mechanisms involved in these key processes will allow clinicians to direct effective treatment
Moving from description to action - how can we reduce health inequalities?
Dr William Ball
(School of Nursing, Midwifery & Paramedic Practice)
Unfair and avoidable differences in health between social groups or across social positions can be observed in most health conditions and in most societies around the world. At a time when improvements in life expectancy are stalling and the cost-of-living crisis is biting, a policy response is essential to protect population health. To better understand how we can reduce inequalities and translate this knowledge into policy, we should adopt an interdisciplinary framework incorporating social science theory and counterfactual causal inference methods.
Chronic activation of GPR55 with ML184 causes cardiac dysfunction in C57Bl/6J mice
Dr Nadine Godsman
(School of Pharmacy & Life Sciences)
Previous studies show that genetic deletion of GPR55 in mice causes reduced cardiac contractile reserve and maladaptive adrenergic signalling. We investigated the effect of chronic GPR55 activation with agonist ML184 in wild type and GPR55-/- mice. Our in vivo cardiac function measurements indicate that ML184 has a similar deleterious effect as GPR55 deletion and this alters the response to beta 1 adrenoceptor stimulation in vivo. All ML184 effects were evident in wild type mice only, confirming that they were GPR55-mediated. These results indicate the complex role of GPR55 in cardiac function
Map data © OpenStreetMap contributors.