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One in six people over 80 in the UK has dementia, of which Alzheimer's is the most common form. However, Alzheimer's is still poorly understood and researchers at Exeter are actively working to fix that! In this event we'll learn about symptoms of the disease, and how it can be treated.
Epileptic seizures in the memory clinic population: What are they like? Who is having them? When do they occur?
Dr John Baker (Clinical Research Fellow)
Epileptic seizures are an under-recognised feature of dementia. This is surprising given that Alzheimer himself described seizures in a patient with dementia in 1911. However, previous research in this area has provided conflicting results and the prevalence of epilepsy in dementia remains unclear. We measured the prevalence and clinical features of epilepsy in a cohort of patients recruited from a secondary care memory clinic.
Interpreting genes in the progression of Alzheimer’s disease
Isabel Castanho (PhD Student)
Alzheimer’s disease (AD), the most common form of dementia, affects more than 520,000 people in the UK only. Although we know amyloid plaques and tau neurofibrillary tangles build up in AD brains for many years, we still know very little about the changes responsible for the start of AD and how quickly it progresses, which will help the development of methods for both diagnosing and treating AD earlier and more effectively. Using cutting-edge laboratory methods and bioinformatics, I am trying to identify changes in gene activation and regulation associated with progression of AD pathology.