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Diseases... in a dish!

Please note this event takes place on the first floor, sorry there is no step-free access.
Past event - 2024
15 May Doors open 6.30pm
Event 7.00-9.00pm
The Britannia, 1 Allen St, Kensington,
London W8 6UX
Sold Out!
Where do diseases even come from? If you want to find out, join us for an exciting evening learning all about how scientists can take diseases out of the body and study exactly how they work, where they came from and how to detect them in humans.



Playing God - Making Blood Vessels in the Lab

Dr Adam Fellows (Research Fellow)
The contraction and expansion of blood vessels (“contractility”) controls how blood is transported throughout the body. Contractility also underpins the development and treatment of cardiovascular disease, but methods to study contractility in the laboratory are lacking. In this talk, Adam will discuss a new bioengineering technique he has developed which creates miniature, three-dimensional “blood vessels” in order to investigate contractility. This highlights the power of in vitro models and has the potential to transform our scientific approach to cardiovascular disease and beyond.

In Vitro Modelling of the Human Brain

Dr Daniel Reumann (Postdoctoral Research Associate)
The human brain is arguably our most complex organ. However, we know very little about how our brain develops, how it functions - and how diseases which affect our brain emerge.

Using human pluripotent stem cells, we are nowadays able to grow small tissues of the human brain in the laboratory, which are called brain organoids. With this fascinating model system, we are able to study some of the mysteries of our brain. In this talk, I will demonstrate how we use brain organoids to study the dopaminergic system, and what implications this technology might have on society in the future.

Organ-on-a-chip technology: A novel platform to study bacterial adaptations which cause urinary tract infections

Nicholas Yuen (PhD student at Imperial College London)
The talk will briefly outline the significance of urinary tract infections (UTI) and how organ-on-a-chip technology can be used to uncover the clever tricks bacteria use to navigate their host (humans!). Bacteria are extremely sensitive to their environment and will adapt to survive against current antibiotic treatments. The use of organoids (mini lab-grown organs) which mimic organ structure and function can help provide a better understanding of infection development. By connecting organoids in a microfluidic chip, we aim to identify and exploit the mechanisms that bacteria deploy to ascend from the gut, to the bladder and even the kidney. This may provide insight into novel therapeutic strategies to combat treatment-resistant infections!
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Other The Britannia events

2024-05-13 Life in a petri-dish: From cell to organism The Britannia 1 Allen St, Kensington, London, W8 6UX, United Kingdom
2024-05-14 Heartfelt futures: Using cardiology and genetics to predict future illness The Britannia 1 Allen St, Kensington, London, W8 6UX, United Kingdom