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Animals are often used to model human diseases. Tonight, however, we'll provide evidence on how it is possible to conduct high quality research while using alternative approaches which avoid the use of animals. We will hear from Dr Sosabowski about all the false "myths" surrounding animal- tested products and from Dr Vagnoni on how he uses fruit flies to understand neuronal ageing. During the event, there will be Pint of Science T-shirts and bottle openers to be won!
Do no harm …… or at least, as little as possible
Dr Jane Sosabowski (Lecturer in Pre-clinical Molecular Imaging)
How do you feel about the use of animals in scientific research? Do you use cosmetics or toiletries that state on the packaging “Not tested on animals”? Did you know that this practice has been banned since 1998? Is the manufacturer trying to convince you that somehow their product is superior to another similar (but mythical) product that HAS been tested on animals? Similarly, there are many myths surrounding the use of animals in medical research. This talk will look at how we have reduced the numbers of mice used in scientific studies without reducing the value of the results.
Intracellular Motion & neuronal ageing
Dr Alessio Vagnoni (NC3Rs David Sainsbury’s Postdoctoral Fellow)
Constant movement of cellular components keeps our neuronal cells functioning. With age, movements of proteins and organelles slow down. When this process is irreversibly stopped, neuronal functions deteriorate and they eventually die. Inspired by the concept of motion that has pervaded the arts and sciences for millennia, I will show how the idea of movement is intriguingly associated with ageing neurons. Following a simple ad hoc logic, I will demonstrate that the humble fruit fly can provide unprecedented insight into an exceptionally dynamic readout of neuronal ageing.