Other Durham events

How your body tries to kill you, and how worms might be able to help

Please note that this event takes place on the first floor and has no step-free access.
Past event - 2022
11 May Doors: 7pm
Event 7:30-9:30pm
Head of Steam, 3 Reform Place, North Road,
Durham DH1 4RZ
One way your body causes you trouble through the same means that it keeps you alive - dividing cells - and one way scientists are trying to speed up the development of new medicines...

P53 - what happens when a guardian protein goes rogue

Dr. Patricia Muller (Associate Professor (Biosciences))
Cells dividing have to copy their DNA. Small errors when DNA is copied pose a cancer risk. With so many cells in our body maybe we should ask not ‘why do we get cancers?’, but ‘why do we not get cancers?’. More cells should mean a slightly increased risk of developing cancer; this is true for taller humans, but large animals like elephants never develop cancer. Why? Elephants seen to have more of a protein called p53; it can detect DNA errors and order cells to repair them or self-destruct. In most human cancers, p53 itself has errors; we look at how, what that leads to, and what we can do.

Worms: A game-changer for drug discovery

Alana Mullins (Research Scientist, Magnitude Biosciences Ltd)
Developing new medicines is extremely expensive and time-consuming; new approaches are continuously needed to accelerate the process. One approach is to use the microscopic nematode worm, known as C. elegans as a tiny animal to test and discover new drugs. In her talk, Alana will discuss case by case how C. elegans have been used to find new treatments for devastating human diseases.

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