Other London events

Lost connections: Unravelling the mysteries of brain disease

This event has step-free access and an accessible facilities.
Past event - 2024
15 May Doors open 6.30pm
Event 7.00-9.00pm
The Durell Arms, 704 Fulham Road,
London SW6 5SA
Sold Out!
Diseases of the brain are extremely complex and difficult to study - yet their consequences are often severe. Scientists are working to slow down the effects of disease such as Alzheimer's but what if we could get to the root cause and stop these diseases altogether? Come along for an extremely relevant evening of talks, learning from experts in the field about what we know so far.

Investigating lost connections in the Alzheimer’s brain

Dr Johanna Jackson (Advanced Research Fellow, Research Leader, UK DRI Emerging Leader)
We are at a crucial moment in Alzheimer’s Disease research. As therapies are developed to slow the underlying causes of the disease, other treatments, such as those targeting synapses, aim to address the symptoms of the disease. Synapses are small connections where two brain cells meet and communicate, and their loss is associated with disease symptoms. We investigate what happens to synapses during Alzheimer’s Disease in human post mortem tissue in order to develop and test drugs to alleviate disease symptoms.

Identifying the cell types underlying brain disease and cognitive traits

Dr Nathan Skene (UKRI Future Leaders Fellow, Group Leader)
How do we know what cell types cause a brain disease? The conventional approach has been to look at the pathology seen after death, and see which cells are lost. However, there is no reason to believe that the cells which are lost are the ones that caused the disease in the first place: their disapearance might be a symptom rather than a cause. An alternative approach is to use genetic data, and find the cell types associated with specific regions of the genetic code of the disease. In this talk we’ll consider what we can learn from doing this, and what some of the pitfalls are in evaluating whether the associations found imply causality.
Map data © OpenStreetMap contributors.

Other The Durell Arms events

2024-05-14 Voyage within: Navigating the brain and its memories The Durell Arms 704 Fulham Road, London, SW6 5SA, United Kingdom
2024-05-13 Mindscapes and machines: How our brains shape our world The Durell Arms 704 Fulham Road, London, SW6 5SA, United Kingdom