Mini-brains, rats and stats?

Genetics can tell us a lot about the human condition, from disease to personality. But with every one of us containing millions of genetic variants, we have to be careful how we interpret what we see. In Genes, Stats and Rats, statistical geneticist Lynsey Hall uses her juggling balls and guitar to walk, talk, and sing us through some of the biggest challenges facing medical genetics.

Brain tumours, in particular the Glioblastoma presents a poor prognosis and the therapies available are limited and show low efficacy. This talk will explore the brain tumour environment, focusing on the development of a new model – patient-derived mini-brains, also known as brain organoids – to explore the tumour biology, cell-cell interactions and validation of new treatments to target these tumours.