Other Manchester events

Not Just a Bleeding Heart: Replacing Animal Research

This venue has step-free access upon request. Under 18s must be accompanied by an adult.
what3words ///bats.fish.goats
Past event - 2024
14 May Doors open 7pm
Event 7.30pm to 10pm
Hetherington's Cafe Bar, 8 Pollard St,
Manchester M4 7AJ
How do scientists investigate how the heart beats, bodies bleed and blood vessels block, without the use of animals? Find out about innovative approaches replacing animals and improving the predictive power of cardiovascular research.

Clotting and Bleeding: A Double-edged Sword

Dr. Amelia Drysdale (Postdoctoral Research Associate)
Dr. Sarah Jones (Reader)
Cardiovascular disease is the leading cause of death globally, causing almost 18 million deaths a year. 80% of these are due to heart attacks and strokes, caused by blood clots blocking arteries. The same blood clotting processes however are critical to prevent life threatening bleeding. Sarah and Amelia are using animal-free approaches to understand how the body controls blood clotting and bleeding and test new treatments to prevent heart attacks and strokes.

Drug safety in a heartbeat

Dr Andrew Leach (Lecturer in Pharmaceutical Chemistry)
Sylvia Kaempf (PhD Student)
One of the most common reasons for drugs to fail safety testing is side effects that cause issues with the heart, such as an irregular heartbeat. Andrew and Sylvia are developing a computer programme to simulate how drugs affect the ‘wires’ that make the heart muscle pump. With their virtual drug testing, they aim to replace some of the animals used for cardiac safety studies and speed up the development of new drugs.
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