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Alzheimer's Disease (AD) causes memory problems by making synapses disappear. Synapse loss is attributed to the accumulation of a toxic protein, amyloid, but some people have high levels of amyloid without memory loss. Studying these "resilient" individuals could lead to drugs that boost resilience. Wearable devices and artificial intelligence/machine learning (AI/ML) are revolutionizing healthcare, collecting vast amounts of data for analysis. Are we prepared to embrace this technology?
Digital health and the wearable technology revolution
We are at the dawn of a digital healthcare revolution. The tsunami of physiological and behavioural data that now can be collected from smartphones, smartwatches, smartrings, fitness trackers and a rapidly growing array of wearable devices—coupled with the latest advances in artificial intelligence & machine learning (AI/ML)—will change the face of routine healthcare as we know it. Are we ready to embrace this technology?
Why are some brains sturdier than others?
Dr Becky Carlyle (Alzheimer’s Research UK Senior Research Fellow and Departmental Research Lecturer, Department of Physiology, Anatomy and Genetics)
To make memories, brain cells must communicate through a junction called the synapse. In Alzheimer’s Disease, synapses disappear, causing problems making memories. It has long been thought that synapse loss stems from accumulation of a toxic protein called amyloid. We’ve recently realized there are a significant number of people with a lot of amyloid in their brains who have no memory loss or outward signs of Alzheimer’s Disease. We call these people resilient, and we’re investigating what protects their synapses, and whether we can design drugs that help to boost resilience in other people.
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Other James St. Tavern events
2023-05-23 Aging with grace: a tale of worms and knees James St. Tavern 47-48 James Street, Oxford, Oxfordshire, OX4 1EU, United Kingdom
Aging with grace: a tale of worms and knees
2023-05-24 Breaking through medical barriers: advancing treatments from the brain to the spine James St. Tavern 47-48 James Street, Oxford, Oxfordshire, OX4 1EU, United Kingdom