Geneticists are interesting .. I promise!

Join Amy as she discusses exactly how she got into the field of bioinformatics and cancer genetic - from Shanghai to Cardiff. She'll also touch on how she's using bioinformatics to find novel predisposition genes for colorectal polyposis. Grab a pint for this introduction to the night!

Genomes contain the genetic information of organisms and are written in the four famous nucleotides: A, T, C and G. Knowing the sequence of nucleotides of every genome became the 20th century geneticist’s dream. The development of the (now called) first-generation sequencing methods and novel computational approaches allowed the generation of the first draft sequence of the human genome in 2001. Grab a pint and find out what advances have happened since then and how we utilise them for disease, discovery and more!

All the different cell-types in the human body, from brain cells, to blood cells and even hair producing cells, share the same common starting ancestor (fertilised egg) and the same instruction manual (genomic DNA). This vast array of specialised cell-types arises through highly orchestrated gene expression patterns that are hard-wired into our DNA. In this talk we will consider new research describing how the 3D genome regulates gene expression to ensure the correct genes are expressed at the right time in the right cell-type.